Primary Prevention of Variceal Hemorrhage
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Emmanuel A. Tsochatzis & Christos K. Triantos & Matteo Garcovich & Andrew K. Burroughs
- چاپ و سال / کشور: 2010
Description
Variceal hemorrhage is one of the leading causes of death in patients with cirrhosis, with the 6-weekmortality after each episode ranging from 15% to 20%. The two main strategies for primary prevention of variceal bleeding in patients with cirrhosis and varices are the administration of nonselective â-blockers or the obliteration of varices with use of endoscopic band ligation. In this review, we present and critically review the latest data on primary prevention of variceal hemorrhage. We advocate that nonselective â-blockers should be the first line therapy, and band ligation should be offered only in cases of intolerance or side effects. We also explore potential future therapies based on preliminary experimental and clinical data.
Curr Gastroenterol Rep (2011) 13:3–9 DOI 10.1007/s11894-010-0160-x Published online: 19 November 2010
