GERD-Related Cough: Pathophysiology and Diagnostic Approach
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Jaclyn A. Smith & Rayid Abdulqawi & Lesley A. Houghton
- چاپ و سال / کشور: 2011
Description
Chronic cough is a common problem resulting in significant impairment of quality of life. Along with cough variant asthma and nasal disease, gastroesophageal reflux is considered one of three main causes of cough. Despite this, acid suppression therapy is often far from effective. This review aims to explore whether reflux can lead to cough, the circumstances in which this is most likely to occur, and the potential mechanisms linking these processes. Particular mechanisms to be explored include laryngopharyngeal reflux, microaspiration, and neuronal cross-organ sensitization. Finally, diagnostic approaches are considered.
Curr Gastroenterol Rep (2011) 13:247–256 DOI 10.1007/s11894-011-0192-x Published online: 5 April 2011
