Pulmonary Vasodilation in Acute and Chronic Heart Failure: Empiricism and Evidence
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Maya Guglin
- چاپ و سال / کشور: 2011
Description
Pulmonary hypertension in heart failure is associated with exercise intolerance and adverse outcomes. With the availability of multiple drugs that cause pulmonary vasodilation and decrease pulmonary arterial pressure, pulmonary hypertension becomes an attractive therapeutic target. Out of several classes of medications, oral phosphodiesterase inhibitors emerge as the most promising in terms of symptomatic improvement, hemodynamic benefits, reverse cardiac remodeling, and functional capacity. Future trials will show whether the use of these drugs translates to decreased morbidity and mortality in heart failure
Curr Heart Fail Rep (2011) 8:219–225 DOI 10.1007/s11897-011-0061-9 Published online: 10 May 2011
