Impact of Diabetes on Postinfarction Heart Failure and Left Ventricular Remodeling
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Helene von Bibra & Martin St John Sutton
- چاپ و سال / کشور: 2011
Description
Diabetes mellitus, the metabolic syndrome, and the underlying insulin resistance are increasingly associated with diastolic dysfunction and reduced stress tolerance. The poor prognosis associated with heart failure in patients with diabetes after myocardial infarction is likely attributable to many factors, important among which is the metabolic impact from insulin resistance and hyperglycemia on the regulation of microvascular perfusion and energy generation in the cardiac myocyte. This review summarizes epidemiologic, pathophysiologic, diagnostic, and therapeutic data related to diabetes and heart failure in acute myocardial infarction and discusses novel perceptions and strategies that hold promise for the future and deserve further investigation
Curr Heart Fail Rep DOI 10.1007/s11897-011-0070-8 The Author(s) 2011. This article is published with open access at Springerlink.com
