New Immunomodulatory Drugs in Myeloma
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Martha Q. Lacy
- چاپ و سال / کشور: 2010
Description
Multiple myeloma (MM) is an incurable malignancy of plasma cells. The introduction of thalidomide was a milestone in the treatment of MM. Thalidomide analogues termed immunomodulatory drugs (IMiDs) have been developed that are more effective and have less toxicity than thalidomide. The role of lenalidomide in relapsed MM has been well defined. This review discusses the data regarding the upfront use of lenalidomide with dexamethasone or in multidrug combinations, as well as its potential role as maintenance therapy. It also reviews our experience with pomalidomide, a new IMid with remarkable activity in relapsed, refractory MM
Curr Hematol Malig Rep (2011) 6:120–125 DOI 10.1007/s11899-011-0077-y Published online: 16 February 2011
