Time Trends of Mortality from Gastric Cancer in Europe
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Amnon Sonnenberg
- چاپ و سال / کشور: 2011
Description
Background The time trends of gastric and duodenal ulcer disease are shaped by a birth-cohort phenomenon. Aims The aim of this study was to assess the extent by which a birth-cohort phenomenon also affected the long-term time trends of gastric cancer among different European countries. Methods Mortality data from France, Germany, Netherlands, Scotland, Spain, and Sweden of the past 56–85 years were analyzed. The age-specific death rates were plotted against the period of death as period-age contours and against the period of birth as cohort-age contours. Results The long-term time trends of gastric cancer mortality were found to have risen among generations born during the 18th century until the mid-19th century and then to have declined in all subsequent generations. The rise and fall of gastric cancer preceded similar birth-cohort patterns of gastric and duodenal ulcer by about 10–30 years. With the exception of gastric cancer in Germany, similar birthcohort phenomena were found in all countries, as well as in men and women. Conclusions The time trends of mortality from gastric cancer and peptic are shaped by birth-cohort patterns that have affected all countries of Europe. It remains an enigma why mortality associated with gastric cancer and peptic ulcer suddenly started to rise within a short time period during the 19th century.
Dig Dis Sci (2011) 56:1112–1118 DOI 10.1007/s10620-010-1553-2 Received: 10 November 2010 / Accepted: 22 December 2010 / Published online: 14 January 2011
