Peripheral Arthritis in the Course of Inflammatory Bowel Diseases
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : _Ilhami Yu¨ ksel Hilmi Ataseven O¨ mer Bas¸ar Seyfettin Ko¨klu¨ _Ibrahim Ertug˘rul Aysel U¨ lker U¨ lku¨ Dag˘lı Nurgu¨l S¸as¸maz
- چاپ و سال / کشور: 2010
Description
Background Musculoskeletal disorders are well-defined extra-intestinal manifestations of inflammatory bowel diseases (IBD). There is little data regarding the frequencies of IBD and extra-intestinal manifestations from Central and East Europe and Middle Eastern countries. Aims To determine the prevalence of peripheral arthritis in IBD and to document the relationship to other extraintestinal manifestations. Methods Enrolled in the study were 357 patients who were diagnosed with IBD from December 2002 through January 2008. All of the patients underwent a detailed whole-body examination by a gastroenterologist and rheumatologist. Results IBD-related peripheral arthritis (IBDPA) was found in 66 (18.5%) of the 357 patients (28.3% Crohn’s disease, 13.5% ulcerative colitis; p = 0.001 v = 11.62). IBDPA was more frequent in female patients (60.6 vs. 39.4%, p = 0.000, v = 11.12). In eight (12.1%) cases, IBDPA occurred before the onset of IBD. Acute self-limiting episodes, recurrences of the attacks, and persistent symptoms of arthritis were present in 40 (60.6%), 26 (39.3%), and 29 (45.7%) patients, respectively. Arthritis was symmetrical in 33 (50%) cases. Knees (65.2%) and ankles (62.1%) were the most commonly affected joints. Erythema nodosum and pyoderma gangrenosum were more common among patients with IBDPA than patients without it (p = 0.001, v = 10.49, and p = 0.000 v = 25.77, respectively). Conclusions IBDPA is a frequent extra-intestinal complication of IBD. Those of female gender and the presence of Crohn’s disease, erythema nodosum and pyoderma gangrenosum have a higher risk to develop IBDPA.
Dig Dis Sci (2011) 56:183–187 DOI 10.1007/s10620-010-1260-z Received: 6 November 2009 / Accepted: 20 April 2010 / Published online: 11 May 2010
