Is It Worthwhile to Perform Capsule Endoscopy for Asymptomatic Patients with Positive Immunochemical Faecal Occult Blood Test?
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Hideyuki Chiba Masau Sekiguchi Takafumi Ito Yosuke Tsuji Ken Ohata Akiko Ohno Shotaro Umezawa Suguru Takeuchi Kantaro Hisatomi Takum
- چاپ و سال / کشور: 2011
Description
Background The immunochemical faecal occult blood test (IFOBT) is widely performed for colorectal cancer screening, but the usefulness of IFOBT in the detection of disorders of the small intestine is unknown. The objective of this study was to investigate what proportion of IFOBT-positive subjects with negative colonoscopy and oesophagogastroduodenoscopy has pathologies of the small intestine detected by capsule endoscopy (CE). Methods Between October 2008 and June 2010, asymptomatic IFOBT-positive patients with negative total colonoscopy and oesophagogastroduodenoscopy underwent CE. CE findings were classified into three categories: P0 (no abnormalities, or findings without potential for bleeding), P1 (findings with uncertain potential for bleeding), P2 and (findings with high potential for bleeding). Results Fifty-three patients (37 males, 16 females; 52.1 ± 13.0 years) were included. There were no cases with P2, 19 cases with P1, and 34 cases with P0 (there were no abnormalities in 25 of 34 cases). As a result, lesions in the small intestine were detected in 28 cases. Additional examination was considered necessary for five patients after CE, but no abnormality was detected, and therapeutic intervention was not undertaken in any case. Caecal completion rate was 92.5%. Conclusions No significant pathologies of the small intestinewere detected in asymptomatic IFOBT-positive cases with negative colonoscopy and oesophagogastroduodenoscopy CE is of limited use in asymptomatic patients with positive IFOBT.
Dig Dis Sci DOI 10.1007/s10620-011-1798-4 Received: 10 April 2011 / Accepted: 10 June 2011
