Prevalence of rhinosinusitis among atypical cystic Wbrosis patients
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Tal Marshak · Y. Rivlin · L. Bentur · O. Ronen · N. Uri
- چاپ و سال / کشور: 2011
Description
The objective of this paper is to study the correlation between sinonasal involvement and type of cystic Wbrosis (CF) in Israeli’s CF patients. The comparative study includes 70 CF patients: 40 typical and 30 atypical CF patients. History and physical examination data were recorded, including endoscopic nasal examination as well as sinus computer tomography scan. The data collected from the two groups were statistically analyzed. Twentyseven percent of atypical CF patients compared with 2.5% of typical CF patients had CF presenting symptoms of chronic rhinosinusitis (CRS) or obstructive nasal polyps (p < 0.001). Although severe CRS was found slightly more often in patient with atypical CF (43 vs. 32.5%), this diVerence did not reach statistical signiWcance. Nine patients with severe CRS underwent endoscopic sinus surgery. Among these patients, six (66.6%) had atypical CF and only three (33.3%) had typical CF (p = 0.09). In conclusion, severe CRS is a common diagnosis among patients with typical and atypical CF disease. In the current study, no signiWcant diVerence in the frequency of CRS was found between the two groups. High awareness toward the diagnosis of atypical CF, careful medical history focusing on sinonasal involvement and physical examination, including nasal endoscopy, for all CF patients (typical and atypical CF) may contribute to an early detection and treatment of signiWcant sinonasal involvement, and may improve the quality of life of the patients.
Eur Arch Otorhinolaryngol (2011) 268:519–524, Received: 10 April 2010 / Accepted: 2 September 2010 / Published online: 15 September 2010 © Springer-Verlag 2010
