Photodynamic therapy of early stage oral cavity and oropharynx neoplasms: an outcome analysis of 170 patients
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Baris Karakullukcu · Kim van Oudenaarde · Marcel P. Copper · W. M. C. Klop · Robert van Veen · Maarten Wildeman · I. Bing Tan
- چاپ و سال / کشور: 2011
Description
The indications of photodynamic therapy (PDT) of oral cavity and oropharynx neoplasms are not well deWned. The main reason is that the success rates are not well established. The current paper analyzes our institutional experience of early stage oral cavity and oropharynx neoplasms (Tis-T2) to identify the success rates for each subgroup according to T stage, primary or non-primary treatment and subsites. In total, 170 patients with 226 lesions are treated with PDT. From these lesions, 95 are primary neoplasms, 131 were non-primaries (recurrences and multiple primaries). The overall response rate is 90.7% with a complete response rate of 70.8%. Subgroup analysis identiWed oral tongue, Xoor of mouth sites with more favorable outcome. PDT has more favorable results with certain subsites and with previously untreated lesions. However, PDT can Wnd its place for treating lesions in previously treated areas with acceptable results.
Eur Arch Otorhinolaryngol (2011) 268:281–288, Received: 13 April 2010 / Accepted: 2 August 2010 / Published online: 13 August 2010 © The Author(s) 2010. This article is published with open access at Springerlink.com
