MRI-derived tumor thickness: an important predictor of outcome for T4a-staged tongue carcinoma
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Wei-Lin Chen Chin-Chuan Su Chih-Ming Chen Ming-Che Lee Hui-Chuan Chen Mu-Kuan Chen
- چاپ و سال / کشور: 2011
Description
The objectives of this paper are to evaluate the heterogeneity of magnetic resonance imaging (MRI)- derived tumor thickness within tumors of the same T4astaged tongue carcinoma and to elucidate the effects of tumor thickness on treatment outcomes. A sequential and prospectively maintained head and neck cancer database was retrospectively searched for newly diagnosed tongue carcinoma treated with surgery between 2003 and 2006. Fifty-eight patients with newly diagnosed T4a-staged tongue carcinoma were included in this study. Tumor thickness was obtained from preoperative magnetic resonance imaging. The mean MRI-derived tumor thickness was 22.29 mm. The patients with long tumor thickness ([26 mm) were associated with a significantly poor disease- specific survival (P = 0.015). The 2-year diseasespecific survival rates were 72% in patients with short tumor thickness and only 27% in patients with long tumor thickness within the same T4a-staged disease. A substantial variation in MRI-derived tumor thickness was present within the same T4a-staged tongue carcinoma, and tumor thickness represented an important prognostic factor
Eur Arch Otorhinolaryngol, Received: 21 March 2011 / Accepted: 21 June 2011 Springer-Verlag 2011
