Cerebrospinal fluid diagnostics in first-episode schizophrenia
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Laura Kranaster • Dagmar Koethe • Carolin Hoyer • Andreas Meyer-Lindenberg • F. Markus Leweke
- چاپ و سال / کشور: 2011
Description
We evaluated the clinical use and the safety of cerebrospinal fluid diagnostics in 155 patients with the suspected diagnosis of first-episode schizophrenia. Five patients (3.2%) revealed pathological findings that lead to diagnostic re-evaluation and changes in clinical management. No serious adverse events occurred, but we documented 16 (10.3%) cases of mild to moderate headache or local pain at the puncture site. Our results underline the value of lumbar puncture in the clinical workup of firstepisode patients with suspected schizophrenia
Eur Arch Psychiatry Clin Neurosci DOI 10.1007/s00406-011-0193-7 Received: 1 October 2010 / Accepted: 20 January 2011