An unusual mimicker of a sepsis outbreak: ergot intoxication
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Ahmet Yagmur Bas & Nihal Demirel & Ahmet Soysal & Kahraman Arslan & Ugur Dilmen
- چاپ و سال / کشور: 2011
Description
Methylergonovine (MEV) is a semi-synthetic ergot alkaloid used in the prevention and control of postpartum hemorrhage. This report describes 12 newborns born on the same day in a local country hospital in Turkey and developed sepsis-like symptoms and encephalopathy within the first 6 h of life due to accidental administration of MEV instead of vitamin K in the delivery room. The major features of MEV poisoning were lethargy (41.7%), seizure (75.0%), feeding intolerance (66.6%), hypoventilation (58.3%), irritability (25%), and peripheral circulatory abnormalities (58.3%). As a conclusion, clinical findings of ergot toxicity in newborns cannot be distinguished from infectious disease or neonatal encephalopathy.
Eur J Pediatr (2011) 170:633–637 DOI 10.1007/s00431-010-1336-y, Received: 19 July 2010 / Accepted: 11 October 2010 / Published online: 23 October 2010
