The relationship between migraine and right-to-left shunt in children
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Sevcan Sarsoy & ضmer Faruk Aydn &Metin Sungur & Ilkay Koray Bayrak & Servet Aker & Hamit ضzyürek & Haydar Ali Tademir & Kemal Baysal
- چاپ و سال / کشور: 2011
Description
Migraine is the most common headache in childhood, and there are some reports that suggest the relationship between migraine and right-to-left shunt. The aim of this study was to evaluate the frequency of right-toleft shunt in children with migraine with aura and compare it with children with migraine without aura, and in healthy children. In a cross-sectional case–control study, we assessed 20 children with migraine with aura, 20 migraine without aura and 20 healthy age, and gender-matched control group. We determined the frequency of right-to-left shunt by transcranial doppler with contrast and transthoracic echocardiography without contrast. The dopplers and echocardiograms were performed blindly by the same examiners during headache-free periods. The presence of right-to-left shunt was found in 13/20 patients with migraine with aura compared with five of 20 migraine without aura and four of 20 control subjects. The frequency of right-to-left shunt in migraine with aura was statistically different from the other two groups (P<0.005). There was no association between right-to-left shunt and frequency of attacks, duration and intensity of attacks, uni/bilateral occurence, familial occurrence, gender and age of patients. Conclusion: our findings suggest possible association of migraine with aura and right-to-left shunt. It seems that right-to-left shunt does not influence the clinical features of migraine.
Eur J Pediatr (2011) 170:365–370 DOI 10.1007/s00431-010-1303-7, Received: 11 May 2010 / Accepted: 15 September 2010 / Published online: 28 September 2010
