Pyogenic liver abscess and peritonitis due to Rhizopus oryzae in a child with Papillon–Lefevre syndrome
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Buket Dalgic & Aysegul Bukulmez & Sinan Sari
- چاپ و سال / کشور: 2011
Description
Papillon–Lefevre syndrome (PLS) is an autosomal recessive disease that is characterized by symmetric palmoplantar keratodermatitis and severe periodontal destruction. Mutations in the cathepsin C gene (CTSC) have recently been detected in PLS. Immune dysregulation, due to a mutation in CTSC, increases the risk of pyogenic infections in PLS patients. A child with PLS is presented here with liver abscesses and peritonitis caused by Rhizopus oryzae. His liver abscess and peritonitis were cured with amphotericin B without surgical care. This is the first case in the literature liver abscess due to Rhizopus oryzae in a child with PLS
Eur J Pediatr (2011) 170:803–805 DOI 10.1007/s00431-010-1368-3 Received: 5 October 2010 / Accepted: 24 November 2010 / Published online: 17 December 2010
