Four-dimensional computed tomography: a method of assessing right ventricular outflow tract and pulmonary artery deformations throughout the cardiac cycle
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Silvia Schievano & Claudio Capelli & Carol Young & Philipp Lurz & Johannes Nordmeyer & Catherine Owens & Philipp Bonhoeffer & Andrew M. Taylor
- چاپ و سال / کشور: 2010
Description
Objective To characterise 3D deformations of the right ventricular outflow tract (RVOT)/ pulmonary arteries (PAs) during the cardiac cycle and estimate the errors of conventional 2D assessments. Methods Contrast-enhanced, ECG-gated cardiovascular computed tomography (CT) findings were retrospectively analysed from 12 patients. The acquisition of 3D images over 10 phases of the cardiac cycle created a four-dimensional CT (4DCT) dataset. The datasets were reconstructed and deformation measured at various levels of the RVOT/PAs in both space and time. Section planes were either static or dynamic relative to the motion of the structures. Results 4DCT enabled measurement and characterisation of in vivo 3D changes of patients’ RVOT/PA during the cardiac cycle. The studied patient population showed a wide range of RVOT/PA morphologies, sizes and dynamics that develop late after surgical repair of congenital heart disease. There were also significant differences in the measured cross-sectional areas of the structures between static and dynamic section planes (up to 150%, p<0.05) secondary to large 3D displacements and rotations. Conclusions 4DCT imaging data suggest high variability in RVOT/PA dynamics and significant errors in deformation measurements if 3D analysis is not carried out. These findings play an important role for the development of novel percutaneous approaches to pulmonary valve intervention.
Eur Radiol (2011) 21:36–45 DOI 10.1007/s00330-010-1913-5 Received: 14 April 2010 / Revised: 16 July 2010 / Accepted: 21 July 2010 / Published online: 1 August 2010
