Comparison of T2-weighted and contrast-enhanced T1-weighted MR imaging at 1.5 T for assessing the local extent of cervical carcinoma
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Ayano Akita & Hiroshi Shinmoto & Shigenori Hayashi & Hirotaka Akita & Takuma Fujii & Shuji Mikami & Akihiro Tanimoto & Sachio Kuribayashi
- چاپ و سال / کشور: 2011
Description
Objective To compare two MR sequences at 1.5 T—T2- weighted and contrast-enhanced T1-weighted images—by using macroscopic sections to determine which image type enables the most accurate assessment of cervical carcinoma. Methods Forty consecutive patients (mean age, 39.2 years) with biopsy-proven cervical carcinoma were included. Each MR sequence was assessed for tumour localisations, tumour margins, and cancer extent with the consensus of two readers, and tumour margins were rated on a five-point scale. MR findings were correlated with histopathological findings. Contrast-to-noise ratios (CNRs) obtained with each image were compared using nonparametric tests. Results Thirty-one of 40 patients underwent hysterectomies and nine of 40 underwent trachelectomies. In 36 patients, lesions were identified on at least one sequence. The tumours at stage 1B or higher were detected in 94.7% on contrast-enhanced T1-weighted images and in 76.3% on T2-weighted images (P<0.05). Tumour margins appeared significantly more distinct on contrast-enhanced T1- weighted images than on T2-weighted images (P<0.001). The CNRs obtained using contrast-enhanced T1-weighted images were significantly higher (P<0.001) than those obtained using T2-weighted images. Conclusion Contrast-enhanced T1-weighted imaging is more useful for assessing cervical carcinoma than T2- weighted imaging.
Eur Radiol (2011) 21:1850–1857 DOI 10.1007/s00330-011-2122-6 Received: 14 October 2010 / Revised: 14 February 2011 / Accepted: 18 February 2011 / Published online: 9 April 2011
