Dual-energy-CT of hypervascular liver lesions in patients with HCC: investigation of image quality and sensitivity

Dual-energy-CT of hypervascular liver lesions in patients with HCC: investigation of image quality and sensitivity

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Jens Altenbernd & Till A. Heusner & Adrian Ringelstein & Susanne C. Ladd & Michael Forsting & Gerald Antoch
  • چاپ و سال / کشور: 2010

Description

Objective To investigate dual-energy CT of hypervascular liver lesions in patients with HCC. Methods Forty patients with hepatocellular carcinomas were investigated with abdominal dual-energy CT. In each patient unenhanced and contrast-enhanced imaging with arterial und portovenous delay were performed. Hypervascular lesions were documented on arterial phase 80-kVp images, 140-kVp images, and the averaged arterial images by two radiologists. Subjective image quality (5-point scale, from 5 [excellent] to 1 [not interpretable]) was rated on all images. Results The mean number of hypervascular HCC lesions detected was 3.37±1.28 on 80-kVp images (p<0.05), 1.43± 1.13 on 140-kVp images (p<0.05), and 2.57±1.2 on averaged images. The image quality was 0.3±0.5 for 80-kVp (p<0.05), 1.6±0.5 for 140-kVp (p<0.05) and 3.2±0.4 for the averaged images. Conclusion Low-kVp images of dual-energy datasets are more sensitive in detecting hypervascular liver lesions. However, this increase in sensitivity goes along with a decrease in the subjective image quality of low-kVp images.
Eur Radiol (2011) 21:738–743 DOI 10.1007/s00330-010-1964-7 Received: 29 March 2010 / Revised: 19 August 2010 / Accepted: 20 August 2010 / Published online: 10 October 2010
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