High diagnostic accuracy of prospective ECG-gating 64-slice computed tomography coronary angiography for the detection of in-stent restenosis
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Daniele Andreini & Gianluca Pontone & Antonio L. Bartorelli & Saima Mushtaq & Daniela Trabattoni & Erika Bertella & Sarah Cortinovis & Andrea Annoni &
- چاپ و سال / کشور: 2011
Description
Objectives The accuracy of computed tomography (CT) for assessment of coronary stents is as yet unproven and radiation exposure has been a concern. The aim of our study is to compare radiation dose and diagnostic performance of CT with prospective ECG-triggering versus retrospective ECG-triggering for the detection of in-stent restenosis (ISR). Methods We enrolled 168 consecutive patients with suspected ISR, 83 studied using CT with prospective ECGtriggering (group 1) and 85 using retrospective ECGtriggering (group 2). Results Prevalence of ISR according to catheter angiography was 24% in both groups. The overall evaluability was similar (93% in group 1 vs 95% in group 2). Artefact subanalysis showed a significantly lower number of blooming and higher number of slice misalignment in group 1 vs group 2. In the stent-based analysis using only evaluable stents, specificity, positive predictive value and accuracy were significantly higher in group 1 (100%, 100% and 99%, respectively) than in group 2 (97%, 91% and 95%, respectively, p<0.05). Group 1 was exposed to a lower radiation dose compared with group 2 (4.3±1.4 mSv vs 18.5±5.5 mSv, p<00.1). Conclusions CT with prospective ECG-triggering can improve diagnostic accuracy of non-invasive imaging of coronary stents with a significant reduction in radiation exposure
Eur Radiol (2011) 21:1430–1438 DOI 10.1007/s00330-011-2085-7 Received: 24 August 2010 / Revised: 24 December 2010 / Accepted: 30 December 2010 / Published online: 18 February 2011
