Computer-aided detection of pulmonary embolism at CT pulmonary angiography: can it improve performance of inexperienced readers?
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Kevin N. Blackmon & Charles Florin & Luca Bogoni & Joshua W. McCain & James D. Koonce & Heon Lee & Gorka Bastarrika & Christian Thilo & Philip Costell
- چاپ و سال / کشور: 2011
Description
Purpose To evaluate the effect of a computer-aided detection (CAD) algorithm on the performance of novice readers for detection of pulmonary embolism (PE) at CT pulmonary angiography (CTPA). Materials and Methods We included CTPA examinations of 79 patients (50 female, 52±18 years). Studies were evaluated by two independent inexperienced readers who marked all vessels containing PE. After 3 months all studies were reevaluated by the same two readers, this time aided by CAD prototype. A consensus read by three expert radiologists served as the reference standard. Statistical analysis used ÷2 and McNemar testing. Results Expert consensus revealed 119 PEs in 32 studies. For PE detection, the sensitivity of CAD alone was 78%. Inexperienced readers’ initial interpretations had an average per-PE sensitivity of 50%, which improved to 71% (p<0.001) with CAD as a second reader. False positives increased from 0.18 to 0.25 per study (p=0.03). Per-study, the readers initially detected 27/32 positive studies (84%); with CAD this number increased to 29.5 studies (92%; p=0.125). Conclusion Our results suggest that CAD significantly improves the sensitivity of PE detection for inexperienced readers with a small but appreciable increase in the rate of false positives.
Eur Radiol (2011) 21:1214–1223 DOI 10.1007/s00330-010-2050-x Received: 26 May 2010 / Revised: 19 October 2010 / Accepted: 20 October 2010 / Published online: 13 January 2011
