Feasibility of simultaneous PET/MR imaging in the head and upper neck area
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Andreas Boss & Lars Stegger & Sotirios Bisdas & Armin Kolb & Nina Schwenzer & Markus Pfister & Claus D. Claussen & Bernd J. Pichler & Christina Pfanne
- چاپ و سال / کشور: 2011
Description
Objective The aim of this pilot study was to test and demonstrate the feasibility of simultaneous positron emission tomography (PET) and magnetic resonance imaging (MRI) of the head and upper neck area using a new hybrid PET/MRI system. Methods Eight patients with malignant head and neck tumours were included in the pilot study. Directly after routine PET/CT imaging with a whole-body system using the glucose derivative 2-[18F]fluoro-2deoxy-D-glucose (FDG) as a radiotracer additional measurements were performed with a prototype PET/MRI system for simultaneous PET and MR imaging. Physiological radiotracer uptake within regular anatomical structures as well as tumour uptake were evaluated visually and semiquantitatively (metabolic ratios) in relation to cerebellar uptake on the PET/MRI and PET/CT systems. Results The MR datasets showed excellent image quality without any recognisable artefacts caused by the inserted PET system. PET images obtained with the PET/MRI system exhibited better detailed resolution and greater image contrast in comparison to those fromthe PET/CTsystem. An excellent agreement between metabolic ratios obtained with both PET systems was found: R=0.99 for structures with physiological tracer uptake, R=0.96 for tumours. Conclusion Simultaneous PET/MRI of the head and upper neck area is feasible with the new hybrid PET/MRI prototype.
Eur Radiol (2011) 21:1439–1446 DOI 10.1007/s00330-011-2072-z Received: 18 June 2010 / Revised: 14 December 2010 / Accepted: 20 January 2011 / Published online: 10 February 2011
