Dual-energy CT angiography in peripheral arterial occlusive disease—accuracy of maximum intensity projections in clinical routine and subgroup analysis
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Thomas Kau &Wolfgang Eicher & Christian Reiterer & Martin Niedermayer & Egon Rabitsch & Birgit Senft & Klaus A. Hausegger
- چاپ و سال / کشور: 2011
Description
Objective To evaluate the accuracy of dual-energy CT angiography (DE-CTA) maximum intensity projections (MIPs) in symptomatic peripheral arterial occlusive disease (PAOD). Methods In 58 patients, DE-CTA of the lower extremities was performed on dual-source CT. In a maximum of 35 arterial segments, severity of the most stenotic lesion was graded (<10%, 10–49% and 50–99% luminal narrowing or occlusion) independently by two radiologists, with DSA serving as the reference standard. Results In DSA, 52.3% of segments were significantly stenosed or occluded. Agreement of DE-CTA MIPs with DSA was good in the aorto-iliac and femoro-popliteal regions (ê=0.72; ê=0.66), moderate in the crural region (ê=0.55), slight in pedal arteries (ê=0.10) and very good in bypass segments (ê=0.81). Accuracy was 88%, 78%, 74%, 55% and 82% for the respective territories and moderate (75%) overall, with good sensitivity (84%) and moderate specificity (67%). Sensitivity and specificity was 82% and 76% in claudicants and 84% and 61% in patients with critical limb ischaemia. Conclusion While correlating well with DSA above the knee, accuracy of DE-CTA MIPs appeared to be moderate in the calf and largely insufficient in calcified pedal arteries, especially in patients with critical limb ischaemia.
Eur Radiol (2011) 21:1677–1686 DOI 10.1007/s00330-011-2099-1 Received: 25 October 2010 / Accepted: 29 January 2011 / Published online: 2 March 2011
