Value of MRI and diffusion-weighted MRI for the diagnosis of locally recurrent rectal cancer
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Doenja M. J. Lambregts & Vincent C. Cappendijk & Monique Maas & Geerard L. Beets & Regina G. H. Beets-Tan
- چاپ و سال / کشور: 2011
Description
Objectives To evaluate the accuracy of standard MRI, diffusion-weighted MRI (DWI) and fusion images for the diagnosis of locally recurrent rectal cancer in patients with a clinical suspicion of recurrence. Methods Forty-two patients with a clinical suspicion of recurrence underwent 1.5-T MRI consisting of standard T2- weighted FSE (3 planes) and an axial DWI (b0,500,1000). Two readers (R1,R2) independently scored the likelihood of recurrence; [1] on standard MRI, [2] on standard MRI+DWI, and [3] on T2-weighted+DWI fusion images. Results 19/42 patients had a local recurrence. R1 achieved an area under the ROC-curve (AUC) of 0.99, sensitivity 100% and specificity 83% on standard MRI versus 0.98, 100% and 91% after addition of DWI (p=0.78). For R2 these figures were 0.87, 84% and 74% on standard MRI and 0.91, 89% and 83% with DWI (p=0.09). Fusion images did not significantly improve the performance. Interobserver agreement was ê0.69 for standard MRI, ê0.82 for standard MRI+DWI and ê0.84 for the fusion images. Conclusions MRI is accurate for the diagnosis of locally recurrent rectal cancer in patients with a clinical suspicion of recurrence. Addition of DWI does not significantly improve its performance. However, with DWI specificity and interobserver agreement increase. Fusion images do not improve accuracy.
Eur Radiol (2011) 21:1250–1258 DOI 10.1007/s00330-010-2052-8 Received: 14 October 2010 / Revised: 22 November 2010 / Accepted: 25 November 2010 / Published online: 16 January 2011
