MR enterography versus capsule endoscopy in paediatric patients with suspected Crohn’s disease
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Emanuele Casciani & Gabriele Masselli & Giovanni Di Nardo & Elisabetta Polettini & Luca Bertini & Salvatore Oliva & Irene Floriani & Salvatore Cucchi
- چاپ و سال / کشور: 2010
Description
Objective The aim of this prospective study was to compare the diagnostic yield of MR enterography (MRE) with small-bowel capsule endoscopy (SBCE) in paediatric patients with suspected Crohn’s disease (CD). Methods Paediatric patients with suspected CD were considered eligible to be enrolled in the study. All patients underwent diagnostic work-up including 1.5-T MRE, ileocolonoscopy and oesophagogastroduodenoscopy. SBCE was not performed if MRE showed SB stricture or extraintestinal findings consistent with symptoms. Results Sixty consecutive paediatric patients (36 male; average age 14) were enrolled into the study. A positive diagnosis for CD was made in 19 patients, 29 had a negative result and 12 were affected by other gastrointestinal conditions. SBCE was performed in 37 patients (61.7%); 23 patients were excluded (strictures in five, extraintestinal findings in 11 and parents’ refusal in seven cases). The accuracy, sensitivity, and specificity of MRE and SBCE were 98.3%, 100%, 97.6%, and 91.9%, 90.9%, 92.3%, respectively. Conclusion Both MRE and SBCE are accurate methods for patients with suspected CD. MRE can be used as a primary imaging technique in suspected CD, in that it allows access to the ileal stricture, which forms a contra-indication for SBCE and provides extra-intestinal information.
Eur Radiol (2011) 21:823–831 DOI 10.1007/s00330-010-1976-3 Received: 1 June 2010 / Revised: 19 August 2010 / Accepted: 25 August 2010 / Published online: 5 October 2010
