Patient acceptability of CT colonography compared with double contrast barium enema: results from a multicentre randomised controlled trial of symptomatic patients
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Christian von Wagner & Samuel Smith & Steve Halligan & Alex Ghanouni & Emily Power & Richard J. Lilford & Dion Morton & Edward Dadswell &Wendy Atkin
- چاپ و سال / کشور: 2011
Description
Objectives To determine patient acceptability of barium enema (BE) or CT colonography (CTC). Methods After ethical approval, 921 consenting patients with symptoms suggestive of colorectal cancer who had been randomly assigned and completed either BE (N= 606) or CTC (N=315) received a questionnaire to assess experience of the clinical episode including bowel preparation, procedure and complications. Satisfaction, worry and physical discomfort were assessed using an adapted version of a validated acceptability scale. Nonparametric methods assessed differences between the randomised tests and the effect of patient characteristics. Results Patients undergoing BE were significantly less satisfied (median 61, interquartile range [IQR] 54–67 vs. median 64, IQR 56–69; p=0.003) and experienced more physical discomfort (median 40, IQR 29–52 vs. median 35.5, IQR 25–47; p<0.001) than those undergoing CTC. Post-test, BE patients were significantly more likely to experience ‘abdominal pain/cramps’ (68% vs. 57%; p= 0.007), ‘soreness’ (57% vs. 37%; p<0.001), ‘nausea/vomiting’ (16% vs. 8%; p=0.009), ‘soiling’ (31% vs. 23%; p= 0.034) and ‘wind’ (92% vs. 84%; p=0.001) and in the case of ‘wind’ to also rate it as severe (27% vs. 15%; p<0.001). Conclusion CTC is associated with significant improvements in patient experience. These data support the case for CTC to replace BE.
Eur Radiol DOI 10.1007/s00330-011-2154-y Received: 15 February 2011 / Revised: 31 March 2011 / Accepted: 29 April 2011
