Reevaluation of the effect of Dianxianning on seizure rate of refractory epilepsy as additive treatment in clinical practice
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Liyun He1, Tiancai Wen1, Shiyan Yan1, Runjin Li2, Zufa Liu3, Hui Ren4, Jinmin Liu5, Fengshan Zhang6, Jianzhong Wu7, Jian Liu8
- چاپ و سال / کشور: 2011
Description
We observed the effect of Dianxianning, which was used as additive treatment to treat 206 epilepsy patients, on the epilepsy seizure rate. Based on a multicenter, prospective, randomized, and controlled clinical trial design, we used the seizure rate of epilepsy as the main index. For the treatment group comprising 137 patients, we combined Dianxianning with chemical medicine, which is the basic treatment. For the control group with 69 patients, we added placebo. The results showed that 1) Effect on seizure rate: After a three-month treatment, the seizure rate of the treatment group decreased by 37.84% on average, whereas that of the control group decreased by 13.18% on average. Statistically comparing the two groups, there was a significant difference between these groups (P < 0.05). 2) Effect on seizure frequency: As time passed, the frequency in each group gradually decreased. After a three-month treatment, there was a significant difference between the two groups (P < 0.05). 3) Comparison between the before and after treatment of each group: There was a very significant difference between the two groups (P < 0.0001). The results indicated that, as an additive treatment, Dianxianning has a good effect on controlling the epilepsy seizure rate and frequency management. It is more effective than using chemical medicine alone
Front. Med. 2011, 5(2): 229–234 DOI 10.1007/s11684-011-0139-5 Higher Education Press and Springer-Verlag Berlin Heidelberg 2011
