Early gastric cancer combined with multiple metachronous osteosclerotic bone and bone marrow metastases that responded to chemoradiotherapy
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Masaaki Saito Hirokazu Kiyozaki Fumihiro Chiba Osamu Takata Takayoshi Yoshida Chio Shuto Shigeki Yamada Fumio Konishi
- چاپ و سال / کشور: 2011
Description
We report a 75-year-old woman who suffered multiple metachronous osteosclerotic bone metastases 4 years after a distal gastrectomy for early gastric cancer (EGC). The primary tumor was a poorly differentiated adenocarcinoma, which had invaded the submucosal layer, and only one lymph node metastasis was noted. To the best of our knowledge, cases of EGC combined with metachronous osteosclerotic multiple bone and bone marrow metastases that respond to chemoradiotherapy are very rare. In this case, the multiple bone metastases were diagnosed 4 years after surgery. The patient’s metastatic tumor was successfully treated using S-1, paclitaxel, and camptothecin, with subsequent irradiation. The patient survived for 24 months after the treatment, without having any major symptoms
Gastric Cancer DOI 10.1007/s10120-011-0062-0 Received: 22 September 2010 / Accepted: 17 May 2011
