Primary non-Hodgkin Lymphoma of the Liver Mimicking Metastases

Primary non-Hodgkin Lymphoma of the Liver Mimicking Metastases

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : N. Paschalidis, J. Kalaitzis, M. Voultsos, A. Marinis, S. Rizos
  • چاپ و سال / کشور: 2011

Description

Liver is a common secondary site of lymphomatous involvement in about half of the patients with non- Hodgkin lymphoma. However, primary hepatic lymphoma is extremely rare, especially when presenting with multiple discrete nodular lesions, as in this case. A 73-year-old man presented with a one-month history of anorexia, weight loss and occasional abdominal pain. Abdominal ultrasound and computed tomography revealed multiple nodular lesions in both hepatic lobes. Total colonoscopy and gastroscopy were negative for a primary cancer site. Ultrasoundguided biopsy of the lesions showed a non-Hodgkin lymphoma of medium size B origin cells. Since no other site of lymphoma involvement was found, a primary non-Hodgkin B cell lymphoma was diagnosed. The patient received adjuvant chemotherapy and 12 months later is free of any symptoms. Multiple nodular liver lesions in patient with anorexia and weight loss mimicking secondary metastases of unknown origin should raise the clinical suspicion for a primary hepatic lymphoma.
Hellenic Journal of Surgery 2011; 83: 1 Received 07/10/2010 Accepted 15/01/2011
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