The treatment of chondral and osteochondral defects of the knee with autologous matrix-induced chondrogenesis (AMIC): method description and recent developments
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Jan Philipp Benthien • Peter Behrens
- چاپ و سال / کشور: 2011
Description
Purpose Articular resurfacing by treatment of chondral defects may include chondral abrasion, autologous chondrocyte Implantation (ACI), matrix-induced chondrocyte transplantation (MACT) or osteochondral autologous transplantation (OATS). This technical note describes the method of autologous matrix-induced chondrogenesis (AMIC), a one-step procedure combining subchondral microfracture with the fixation of a collagen I/III membrane with fibrin glue or sutures. Methods This is a technical note on the AMIC procedure and its further development. Results and conclusion This method is applied primarily in chondral or osteochondral lesions of the knee. Indications and contraindications are provided; the technique is described. The further development of AMIC is described with an increased focus on the subchondral zone and the complex of cartilage and bone, the osteochondral unit, which receives increased attention in cartilage research. Level of evidence IV.
Knee Surg Sports Traumatol Arthrosc (2011) 19:1316–1319 DOI 10.1007/s00167-010-1356-1 Received: 18 July 2010 / Accepted: 6 December 2010 / Published online: 14 January 2011
