Cytomorphological changes in buccal mucosa of patients treated with low-level 1,064-nm laser radiation
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Ufuk Sezer & Mutan Hamdi Aras & Ali Murat Aktan & Beyhan Cengiz & Nadide ضzkul & Sinan Ay
- چاپ و سال / کشور: 2011
Description
The aim of this study was to examine the cytomorphological changes occurring in the buccal mucosa in patients treated with low-level 1,064-nm laser radiation. Seventeen individuals (12 males, five females) 18–24 years of age were included in the study. Low-level 1,064-nm laser radiation was applied to the right buccal mucosa near the premolar region; this therapy was repeated for 10 days. Buccal epithelial cells were collected from the right and left premolar regions of the individuals with a brush before and after therapy. The specimens collected from the left side were measured cytomorphometrically and used for the control group. Student’s t test was used for statistical comparison of the values of the buccal epithelial cells collected from individuals; a p value<0.05 was considered statistically significant. None of the patients showed any adverse reactions to the low-level 1,064-nm laser radiation therapy during application. There was no cytogenetic damage to the therapied or non-therapied regions in the buccal mucosa cells, as determined cytomorphologically. The results suggest that low-level 1,064-nm laser radiation therapy has no genotoxic potential. Within the limitations of this study, it can be concluded that low-level 1,064-nm laser radiation therapy may be used safely in dental treatments.
Lasers Med Sci DOI 10.1007/s10103-011-0947-5 Received: 21 December 2010 / Accepted: 8 June 2011