Reproducibility of subregional trabecular bone micro-architectural measures derived from 7-Tesla magnetic resonance images
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Gregory Chang · Ligong Wang · Guoyuan Liang · James S. Babb · Punam K. Saha · Ravinder R. Regatte
- چاپ و سال / کشور: 2011
Description
High-resolution magnetic resonance imaging (MRI) of trabecular bone combined with quantitative image analysis represents a powerful technique to gain insight into trabecular bone micro-architectural derangements in osteoporosis and osteoarthritis. The increased signal-to-noise ratio of ultra high-field MR (.7 Tesla) permits images to be obtained with higher resolution and/or decreased scan time compared to scanning at 1.5/3T. In this small feasibility study, we show high measurement precision for subregional trabecular bone micro-architectural analysis performed on 7T knee MR images. The results provide further support for the use of trabecular bone measures as biomarkers in clinical studies of bone disorders.
Magn Reson Mater Phy (2011) 24:121–125 DOI 10.1007/s10334-010-0243-6 Received: 21 October 2010 / Revised: 6 December 2010 / Accepted: 21 December 2010 / Published online: 9 January 2011 © ESMRMB 2011
