Constipation triggered the malignant syndrome in Parkinson’s disease
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Emina Ogawa • Ryuji Sakakibara • Masahiko Kishi • Fuyuki Tateno
- چاپ و سال / کشور: 2011
Description
A 69-year-old, chronically constipated patient with Parkinson’s disease developed fecal impaction and the malignant syndrome simultaneously, even while the patient was taking anti-parkinsonian drugs as prescribed. Administration of intravenous levodopa and oral Dai-kenchu-tou, an herbal medicine with serotonergic 5-HT3 receptor agonistic property successfully ameliorated his clinical symptoms. Constipation may trigger worsening of Parkinson’s disease and occurrence of the malignant syndrome by affecting levodopa absorption. Further, improved bowel motility may prevent worsening of Parkinson’s disease and occurrence of the malignant syndrome.
Neurol Sci DOI 10.1007/s10072-011-0710-5 Received: 6 March 2011 / Accepted: 6 July 2011
