Using 18F-FDG PET/CT to Detect an Occult Mesenchymal Tumor Causing Oncogenic Osteomalacia
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Hyo Jung Seo & Yun Jung Choi & Hyun Jeong Kim & Yong Hyu Jeong & Arthur Cho & Jae Hoon Lee & Mijin Yun & Jong Doo Lee &Won Jun Kang
- چاپ و سال / کشور: 2011
Description
Oncogenic osteomalacia is a rare paraneoplastic syndrome characterized by renal phosphate excretion, hypophosphatemia, and osteomalacia. This syndrome is often caused by tumors of mesenchymal origin. Patients with oncogenic osteomalacia have abnormal bone mineralization, resulting in a high frequency of fractures. Tumor resection is the treatment of choice, as it will often correct the metabolic imbalance. Although oncogenic osteomalacia is a potentially curable disease, diagnosis is difficult and often delayed because of the small size and sporadic location of the tumor. Bone scintigraphy and radiography best characterize osteomalacia; magnetic resonance imaging findings are nonspecific. Here, we report a case of oncogenic osteomalacia secondary to a phosphaturic mesenchymal tumor that was successfully detected by 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT). This case illustrates the advantages of 18F-FDG PET/CT in detecting the occult mesenchymal tumor that causes oncogenic osteomalacia
Nucl Med Mol Imaging DOI 10.1007/s13139-011-0095-7 Received: 25 March 2011 / Accepted: 29 June 2011
