Change in Predicted 10-Year Cardiovascular Risk Following Roux-en-Y Gastric Bypass Surgery: Who Benefits?
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Simara P. Donadelli & Wilson Salgado Jr. & Julio S. Marchini & Andre Schmidt & Cristiana A. F. Amato & Reginaldo Ceneviva & Jose Ernesto Dos Santos &
- چاپ و سال / کشور: 2011
Description
Background The risk of developing cardiovascular disease is higher in obese than in non-obese individuals. Surgery for obesity is effective in reducing weight and resolution of diabetes, hypertension, and dyslipidemia. Our aim was to assess the estimated 10-year cardiovascular risk of obese patients before and after treatment of obesity with a gastric bypass. Methods Weight, body mass index systolic and diastolic blood pressure, lipid profile, glycemia, and history of cardiovascular disease were obtained for obese patients before and 2 years after Roux-en-Y gastric bypass surgery. Ten-year cardiovascular risk was calculated using the Framingham score. Results Forty-two patients were included in the study. We observed a significant reduction (p<0.05) of 10-year cardiovascular risk mainly associated with weight reduction and improvement of comorbidities associated with obesity. The benefits were greater among patients who already presented known risk factors such as diabetes and hypertension. Superobese patients benefited as early as 2 years after surgery, when weight loss was greater. Conclusions Weight loss secondary to surgery was sustained after 2 years and promoted improvement of comorbidities, with an important reduction of 10-year cardiovascular risk especially among patients with previous risk factors.
OBES SURG (2011) 21:569–573 DOI 10.1007/s11695-010-0348-z Published online: 7 January 2011
