Reduced Phenytoin Levels in an Epileptic Patient following Roux-En-Y Gastric Bypass for Obesity
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Dimitrios J. Pournaras & David Footitt & David Mahon & Richard Welbourn
- چاپ و سال / کشور: 2010
Description
Despite widespread uptake of bariatric procedures for severe obesity, changes in pharmacodynamics after surgery are poorly understood. We report an epileptic patient who had a seizure following gastric bypass, although he had been asymptomatic for 30 years and without any change in his treatment. Phenytoin levels were undetectable despite a high dose. Drugs with a narrow therapeutic range such as phenytoin should be prescribed with caution after bariatric surgery.
OBES SURG (2011) 21:684–685 DOI 10.1007/s11695-010-0107-1 Published online: 26 February 2010
