Ring fi bers visualized by electron microscopy in a Japanese patient with malignant hyperthermia
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Yoshimasa Kitagawa · Jun Sato · Masaru Kuriyama Kazuo Sano · Kenji Hashimoto
- چاپ و سال / کشور: 2010
Description
This report describes an episode of malignant hyperthermia (MH) in a 53-year-old Japanese man during general anesthesia that was triggered by isofl urane and succinylcholine. His past history and family history were unremarkable. From our analysis of ten exons, he had no recognizable mutation in the ryanodine receptor gene, but compatible with his MH reaction, he showed positive sensitivity to the Ca-induced Ca-release test. Histochemical and electron microscopic studies of muscle biopsy tissue demonstrated unusual “ring fi bers,” which have never before been reported to be associated with MH. The presence of ring fi bers in this patient might indicate muscle regeneration, suggesting a recovery process from the MH episode.
Odontology (2011) 99:101–104 DOI 10.1007/s10266-010-0141-4 Received: November 25, 2009 / Accepted: June 8, 2010
