Secular decreases in fracture rates 1986–2006 for Manitoba, Canada: a population-based analysis
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : W. D. Leslie & M. Sadatsafavi & L. M. Lix & M. Azimaee & S. Morin & C. J. Metge & P. Caetano
- چاپ و سال / کشور: 2010
Description
Summary We examined trends in fracture rates over 20 years in the Province of Manitoba, Canada. Hip fractures, major low-trauma fractures, and high-trauma fractures declined significantly from 1986 to 2006. Introduction Secular decreases in hip fracture rates have been reported in some countries. Whether this phenomenon applies to other fracture sites is not well described. Methods We used 20 years of data from the Population Health Research Data Repository for the Province of Manitoba, Canada. Age-adjusted fracture rates were calculated for men and women age 50 years and older 1986– 2006 according to fracture site and mechanism (presence/ absence of external injury codes). Generalized linear models with generalized estimating equations were used to derive adjusted annual rates and test for linear change in men and women. Results Major low-trauma fractures (hip, forearm, spine, and humerus) showed a significant annual linear decline in women (-1.2% [95% CI, -0.7% to -1.8%]) and in men (-0.4% [95% CI, -0.7% to -0.2%]). Hip fracture showed a significant annual decline for both sexes, while forearm and humerus fractures showed a significant decline only in women. The only fracture category that did not show a significant annual decline in either sex was the spine. The observed annual reduction in high-trauma fractures was even larger and did not show a sex difference (-1.8% [95% CI, -2.8% to -0.7%]). Conclusion We observed a decrease in both low-trauma and high-trauma fracture rates over the study period. This decline was apparent in years prior to widespread osteoporosis testing or availability of modern pharmacotherapy.
Osteoporos Int (2011) 22:2137–2143 DOI 10.1007/s00198-010-1470-4 Received: 4 August 2010 / Accepted: 14 September 2010 / Published online: 11 November 2010
