Mechanism of Cardioprotection: What Can We Learn from Females?
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Elizabeth Murphy • Claudia Lagranha • Anne Deschamps • Mark Kohr • Tiffany Nguyen • Renee Wong • Junhui Sun • Charles Steenbergen
- چاپ و سال / کشور: 2011
Description
This review examines the mechanism of estrogen signaling in cardiomyocytes, with an emphasis on mechanisms that might be important in cardioprotection. It investigates estrogen signaling mediated by the nuclear estrogen receptors alpha and beta and the G-protein-coupled receptor (GPR 30/GPER). Estrogen signaling via nitric oxide and the PI3K pathway are discussed.
Pediatr Cardiol (2011) 32:354–359 DOI 10.1007/s00246-010-9877-4 Received: 13 December 2010 / Accepted: 15 December 2010 / Published online: 29 January 2011
