Post-streptococcal acute glomerulonephritis in children: clinical features and pathogenesis
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : T. Matthew Eison & Bettina H. Ault & Deborah P. Jones & Russell W. Chesney & Robert J. Wyatt
- چاپ و سال / کشور: 2011
Description
Post-streptococcal acute glomerulonephritis (PSAGN) is one of the most important and intriguing conditions in the discipline of pediatric nephrology. Although the eventual outcome is excellent in most cases, PSAGN remains an important cause of acute renal failure and hospitalization for children in both developed and underdeveloped areas. The purpose of this review is to describe both the typical and less common clinical features of PSAGN, to outline the changes in the epidemiology of PSAGN over the past 50 years, and to explore studies on the pathogenesis of the condition with an emphasis on the search for the elusive nephritogenic antigen.
Pediatr Nephrol (2011) 26:165–18 DOI 10.1007/s00467-010-1554-60 Received: 10 March 2010 /Revised: 16 April 2010 /Accepted: 19 April 2010 /Published online: 23 July 2010
