Hepatic and pulmonary nodular lesions in pediatric urinary  tract infections

Hepatic and pulmonary nodular lesions in pediatric urinary tract infections

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Hyung Eun Yim & Byung Min Choi & Young Jun Rhie & Kee Hwan Yoo & Young Sook Hong & Joo Won Lee
  • چاپ و سال / کشور: 2011

Description

One of the major goals in investigating children with urinary tract infection (UTI) is to recognize patients at risk of further UTI-related problems. This study reports the clinical features of 19 pediatric patients with UTIs in whom associated hepatic and/or pulmonary nodules were incidentally diagnosed by the imaging tests performed for the UTI. Hepatic nodules in five patients were detected on ultrasound scans, and pulmonary nodules and both hepatic and pulmonary nodules were detected in 12 and two children by dimercaptosuccinic acid scintigraphy. The mean age of the patients was 24.5 months. Vesicoureteral reflux (VUR) was detected in nine of 17 patients (52.9%), acute pyelonephritis was identified in nine of 18 patients, and renal scarring was found in 57.1% patients with pyelonephritis. On follow-up, the hepatic and/or pulmonary nodules regressed in all patients. About 85.7% of patients experienced a recurrence of UTI within 1 year. In comparison with ageand sex-matched controls with UTIs without pulmonary or hepatic nodules, the presence of VUR and the recurrence of UTI within 1 year were higher in patients with UTIs and nodules (P<0.05). The hepatic and/or pulmonary nodules identified on the ultrasound scan and by dimercaptosuccinic acid scintigraphy may provide a valuable diagnostic marker for the proper management of patients with an UTI.
Pediatr Nephrol (2011) 26:425–431 DOI 10.1007/s00467-010-1706-8 Received: 9 July 2010 / Revised: 2 November 2010 / Accepted: 4 November 2010 / Published online: 19 December 2010
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