Diffusion-weighted MRI of exercise-induced acute renal  failure (ALPE)

Diffusion-weighted MRI of exercise-induced acute renal failure (ALPE)

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Kazuhide Ohta & Tadafumi Yokoyama & Masaki Shimizu & Kazunori Mizuno & Shinobu Sakazume & Takuma Fujiki & Yutaka Saikawa & Akihiro Yachie
  • چاپ و سال / کشور: 2011

Description

Acute renal failure with severe loin pain induced by anaerobic exercise (ALPE) is a rare condition that is accompanied by wedge-shaped contrast enhancement on computed tomography (CT) without evidence of rhabdomyolysis. In two pediatric cases with ALPE, we tried to determine the relationship between findings from CT and magnetic resonance imaging (MRI). Case 1 involved a 13- year-old Japanese girl with a diagnosis of ALPE with normo-uricemia. Contrast-enhanced CT after 24 and 48 h showed a wedge-shaped excretion delay for the contrast media. A clear wedge-shaped signal hyperintensity matching the CT images was obtained by diffusion-weighted MRI. Case 2 involved a 16-year-old boy who presented with a second attack of ALPE after diagnosis of ALPE with hypouricemia 1 year earlier. Only diffusion-weighted imaging was performed. Clear wedge-shaped signal hyperintensity was apparent, similar to Case 1. MRI is safer than contrastenhanced CT for patients with ALPE. Diffusion-weighted MRI is a very useful examination for diagnosing ALPE, providing noninvasive detection of lesions peculiar to ALPE.
Pediatr Nephrol (2011) 26:1321–1324 DOI 10.1007/s00467-011-1869-y Received: 13 September 2010 / Revised: 12 March 2011 / Accepted: 14 March 2011 / Published online: 20 May 2011
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