Molecular thermodynamics of precipitation
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Francesco Fornasiero a,b, Jan Ulrich a,b,1, J.M. Prausnitz a,b,*
- چاپ و سال / کشور: 1999
Description
Using a simple theory for fluids and a simple theory for a solid, it is possible to construct a semi-quantitative correspondingstates phase diagram where a reduced temperature is plotted as a function of a reduced density. The reducing parameters are molecular size (s3) and molecular potential energy (o:kB); the phase diagram includes both low-density and high-density fluid regions and the solid region. These calculations apply to a pure substance or, of more interest, to a solute dissolved in a continuous solvent. The qualitative nature of the phase diagram depends strongly on the range of attractive intermolecular forces as indicated by an exponential parameter n; when coordination number z 8 and n is about 6, we obtain the usual phase diagram where the fluid–solid region lies to the right of the fluid–fluid coexistence curve. But when n is about 7 or 8, the fluid–solid region lies above the fluid–fluid coexistence curve. Applications are discussed for aqueous solutions of a colloid or a globular protein that may also contain a salt or a polymer to induce precipitation
Chemical Engineering and Processing 38 (1999) 463–475 Received 25 March 1999; accepted 12 April 1999
