Vaginal Recurrence More than 17 Years after Hysterectomy and Adjuvant Treatment for  Uterine Carcinoma with Successful Salvage Brachytherapy: A Case Report

Vaginal Recurrence More than 17 Years after Hysterectomy and Adjuvant Treatment for Uterine Carcinoma with Successful Salvage Brachytherapy: A Case Report

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Raphael Yechielia Jared R. Robbinsa Daniel Schultzb Adnan Munkarahc Mohamed A. Elshaikha
  • چاپ و سال / کشور: 2011

Description

Purpose: Although the majority of recurrences occur within the first 3 years of hysterectomy for endometrioid carcinoma, we report herein a successful salvage vaginal brachytherapy in a patient with endometrioid uterine carcinoma which recurred more than 17 years after initial treatment. Materials and Methods: A 61-year-old female was diagnosed with endometrioid adenocarcinoma of the uterus and treated with TAH-BSO, followed by adjuvant external beam radiation therapy (EBRT) to the whole pelvis. After remaining free of any recurrent or metastatic disease for more than 17 years, she was diagnosed with isolated vaginal cuff recurrence and successfully treated with a salvage high-dose-rate intracavitary vaginal brachytherapy. Results: The patient remained disease free until her death from unrelated causes 7 years later. Conclusion: To the best of our knowledge, this case represents the longest time to recurrence of endometrial cancer in someone who had been treated with TAH-BSO and adjuvant pelvic EBRT. This case highlights that even with adjuvant therapy, late recurrences may occur, and successful salvage brachytherapy is very effective.
Case Rep Oncol 2011;4:242–245 DOI: 10.1159/000328076 Published online: April 18, 2011 © 2011 S. Karger AG, Basel ISSN 1662–6575 www.karger.com/cro
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