Microarray-Based Gene Expression Analysis of Hepatocellular Carcinoma
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Thorsten Maass, Ioannis Sfakianakis, Frank Staib, Markus Krupp, Peter R. Galle and Andreas Teufel*
- چاپ و سال / کشور: 2010
Description
Microarray studies have successfully shed light on various aspects of the molecular mechanisms behind the development of hepatocellular carcinoma (HCC), such as the identification of novel molecular subgroups and the genetic profiles associated with metastasis and venous invasion. These experiments, mainly comprising genome wide profiling, potentially represent the basis of novel targeted therapeutic strategies in HCC. In response, we summarize the multiple reported expression profiles in HCC associated with HCC development, novel subgroups, venous invasion and metastasis.
Current Genomics, 2010, 11, 261-268 Received on: October 09, 2009 - Revised on: November 13, 2009 - Accepted on: January 06, 2010
