Longevity Genomics Across Species
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Matt Kaeberlein
- چاپ و سال / کشور: 2007
Description
Unbiased genome-wide studies of longevity in S. cerevisiae and C. elegans have led to the identification of more than one hundred genes that determine life span in one or both organisms. Key pathways have been uncovered linking nutrient and growth factor cues to longevity. Quantitative measures of the degree to which aging is evolutionary conserved are now possible. A major challenge for the future is determining which of these genes play a similar role in human aging and using that information to develop therapies toward age-associated diseases.
Current Genomics, 2007, 8, 73-78 Received on: February 15, 2007 - Revised on: February 23, 2007 - Accepted on: February 26, 2007
