Patterns of Insertion and Deletion in Mammalian Genomes
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Yanhui Fan, Wenjuan Wang, Guoji Ma, Lijing Liang, Qi Shi and Shiheng Tao
- چاپ و سال / کشور: 2007
Description
Nucleotide insertions and deletions (indels) are responsible for gaps in the sequence alignments. Indel is one of the major sources of evolutionary change at the molecular level. We have examined the patterns of insertions and deletions in the 19 mammalian genomes, and found that deletion events are more common than insertions in the mammalian genomes. Both the number of insertions and deletions decrease rapidly when the gap length increases and single nucleotide indel is the most frequent in all indel events. The frequencies of both insertions and deletions can be described well by power law.
Current Genomics, 2007, 8, 370-378 Received on: September 18, 2007 - Revised on: September 22, 2007 - Accepted on: September 23, 2007
