PDGF-D Signaling: A Novel Target in Cancer Therapy
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Zhiwei Wang, Dejuan Kong, Yiwei Li and Fazlul H. Sarkar*
- چاپ و سال / کشور: 2009
Description
Platelet-derived growth factor-D (PDGF-D) is a newly recognized growth factor that can regulate many cellular processes, including cell proliferation, transformation, invasion, and angiogenesis by specifically binding to and activating its cognate receptor PDGFR-... The functions of PDGF-D in human cancer progression are largely unknown. We discuss here the role of PDGF-D signaling pathway in cancer and how its deregulation is involved in tumor development and progression to metastatic disease
Current Drug Targets, 2009, 10, 38-41
