Evaluation of newcastle disease antibody level after different vaccination regimes in three districts of Amhara Region, Northwestern Ethiopia
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Hailu Mazengia1, Esayas Gelaye2* and Mohamed Nega1
- چاپ و سال / کشور: 2009
Description
Evaluation of the Newcastle Disease (NCD) antibody level after different vaccination regime was conducted on chickens distributed at the age of day-old in three districts of Amahara region using sera analysis. Three vaccination regimes on chicks against Newcastle using live lentogenic stains; Hitchener B1 (at the age of day-old) and La Sota (at the age of 21st and 60th days of age) were used. The overall antibody level of Newcastle disease in vaccinated chickens using Hemagglutination inhibition test (1:8) was 71.1% ranging from 80.4, 73.3 and 63.3% in Dangila, Bahir Dar and Farta districts respectively. Significant difference (p < 0.001, df = 2, c2 = 13.3) in antibody level of Newcastle disease was found among the three districts. The antibody level of Newcastle disease in Lohmann White breeds (70.6%) was lower than that of Red Island Red breeds (72.5%) but no significant difference was detected between breeds (p > 0.05, df = 1, c2 = 0.27). On the other hand, chickens vaccinated three times at 1st , 21st and 60th day of age (78.8%) were found to have higher protective antibody titer than chickens vaccinated twice at 1st and 21st day of age (64.9%) and only at 1st day of age (65.4%). There was significant difference (p < 0.05, df = 2, c2 = 8.2) in antibody level of Newcastle disease among different vaccination regime and frequencies. In conclusion, the results of the present study indicated that the protective antibody titer response was produced from these vaccines after booster vaccinations. Hence, it is very crucial to vaccinate chickens with the full dose of vaccines against NCD in order to keep protected poultry population.
Journal of Infectious Diseases and Immunity Vol. 1(2), pp. 016-019, December, 2009 Accepted 17 November, 2009
