Screening for the presence of Helicobacter pylori in stool of HIV- positive patients
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Hossein Samadi Kafil1*, Fatemeh Farahi Jahromi1, Bahareh Hajikhani2, Shahin Najar Pirayeh3 and Mohammad Aghazadeh4
- چاپ و سال / کشور: 2011
Description
Helicobacter Pylori is a bacillus that naturally colonizes humans, living in gastric mucus. Association of H. pylori colonization of stomach with chronic gastritis, peptic ulcer and gastric malignancies has been well documented. In this study, we aimed to find presence of H. pylori in stool of HIV infected patients by PCR. 43 patients who had confirmed HIV-infection were subjected. Specific primers for hpaA (flagellar sheath adhesin) and ureB (urea amidohydrolase), of H. pylori were designed and, presence of the genome of H. pylori investigated by PCR method. 35 of the patients (81.39%) had CD4+ count below 200 and H. pylori was found in 30 patients (69.76%). Results show from screening by H. pylori in stool of HIV-infected patients that prevalence of this bacterium in these patients is high. This prevalence is similar to prevalence of H. pylori in HIV-non infected population.
Journal of AIDS and HIV Research Vol. 3(4), pp. 85-87, April 2011 Available online http://www.academicjournals.org/jahr ISSN 2141-2359 ©2011 Academic Journals Accepted 24 February, 2011
