In vitro protein refolding by chromatographic procedures
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Ming Li,a Zhi-Guo Su,a and Jan-Christer Janson
- چاپ و سال / کشور: 2003
Description
In vitro protein refolding is still a bottleneck in both structural biology and in the development of new biopharmaceuticals, especially for commercially important polypeptides that are overexpressed in Escherichia coli. This review focuses on protein refolding methods based on column procedures because recent advances in chromatographic refolding have shown promising results.